Jun Goo Kang Selected Research

herbimycin

10/2015	17-Allylamino-17-demethoxygeldanamycin and Herbimycin A Induce Cell Death by Modulating β-Catenin and PI3K/AKT Signaling in FRO Anaplastic Thyroid Carcinoma Cells.
12/2014	Herbimycin A inhibits cell growth with reversal of epithelial-mesenchymal transition in anaplastic thyroid carcinoma cells.

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Jun Goo Kang Research Topics

Disease

12	Anaplastic Thyroid Carcinoma 05/2017 - 04/2013
9	Type 2 Diabetes Mellitus (MODY) 01/2020 - 01/2010
7	Thyroid Neoplasms (Thyroid Cancer) 11/2020 - 10/2016
4	Obesity 01/2021 - 01/2010
4	Hypoglycemia (Reactive Hypoglycemia) 06/2015 - 01/2011
3	Insulin Resistance 01/2021 - 01/2010
2	Neoplasms (Cancer) 11/2020 - 04/2013
2	Prediabetic State (Prediabetes) 10/2016 - 04/2016
2	Body Weight (Weight, Body) 01/2014 - 02/2012
1	Hypotension (Low Blood Pressure) 01/2022
1	Sarcopenia 01/2020
1	Carotid Artery Diseases 01/2020
1	Tissue Adhesions 01/2018
1	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 02/2017
1	Lymphoma (Lymphomas) 02/2017
1	Shock 01/2017
1	Graves Disease (Basedow Disease) 01/2017
1	Hemorrhage 01/2017
1	Hyponatremia 01/2017
1	Liver Cirrhosis (Hepatic Cirrhosis) 01/2017
1	Thyroid Diseases (Thyroid Disease) 01/2017
1	Graves Ophthalmopathy 01/2017
1	Diabetes Mellitus 03/2016
1	Overweight 06/2015
1	Weight Loss (Weight Reduction) 06/2015
1	Ataxia Telangiectasia (Louis Bar Syndrome) 02/2015
1	Urinary Incontinence 01/2015

Drug/Important Bio-Agent (IBA)

10	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 01/2010
8	Heat-Shock Proteins (Heat-Shock Protein)IBA 11/2020 - 09/2014
8	Proteins (Proteins, Gene)FDA Link 11/2020 - 05/2009
4	LipidsIBA 01/2021 - 07/2009
4	SurvivinIBA 06/2018 - 02/2015
3	Triglycerides (Triacylglycerol)IBA 01/2021 - 07/2009
3	5- (2,4- dihydroxy- 5- isopropylphenyl)- 4- (4- morpholin- 4- ylmethylphenyl)isoxazole- 3- carboxylic acid ethylamideIBA 11/2020 - 02/2015
3	Histone Deacetylase InhibitorsIBA 01/2019 - 02/2015
3	Metformin (Glucophage)FDA LinkGeneric 01/2018 - 01/2014
2	ORALIT (ORS)IBA 01/2021 - 01/2020
2	6- chloro- 9- (4- methoxy- 3,5- dimethylpyridin- 2- ylmethyl)- 9H- purin- 2- ylamineIBA 11/2020 - 10/2016
2	Histone Deacetylases (Histone Deacetylase)IBA 01/2019 - 02/2016
2	evodiamineIBA 01/2019 - 11/2018
2	LC15-0444IBA 01/2018 - 10/2017
2	Dipeptidyl-Peptidase IV InhibitorsIBA 01/2018 - 10/2017
2	glimepiride (Amarel)FDA LinkGeneric 01/2018 - 01/2014
2	Mitogen-Activated Protein Kinase 3IBA 10/2017 - 02/2017
2	Proto-Oncogene Proteins c-bcl-2 (Proto Oncogene Proteins c bcl 2)IBA 10/2017 - 05/2017
2	Paclitaxel (Taxol)FDA LinkGeneric 05/2017 - 04/2015
2	Mitogen-Activated Protein KinasesIBA 05/2017 - 05/2009
2	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2017 - 02/2017
2	Insulin (Novolin)FDA Link 03/2017 - 01/2014
2	HDL CholesterolIBA 03/2017 - 05/2014
2	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 04/2016 - 06/2015
2	belinostatIBA 02/2016 - 02/2015
2	ApigeninIBA 12/2015 - 04/2013
2	tanespimycin (17AAG)IBA 10/2015 - 04/2015
2	herbimycinIBA 10/2015 - 12/2014
2	Hypoglycemic Agents (Hypoglycemics)IBA 10/2012 - 01/2011
2	Blood Glucose (Blood Sugar)IBA 01/2011 - 08/2010
2	Thioctic Acid (Lipoic Acid)IBA 05/2009 - 01/2009
2	AntioxidantsIBA 05/2009 - 01/2009
1	lipoprotein cholesterolIBA 01/2022
1	Biomarkers (Surrogate Marker)IBA 01/2021
1	Hemoglobins (Hemoglobin)IBA 01/2020
1	Phosphotransferases (Kinase)IBA 06/2018
1	Poloxamer (Poloxamer 407)IBA 01/2018
1	HydrogelsIBA 01/2018
1	Polymethyl Methacrylate (Sol)IBA 01/2018
1	Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA 01/2018
1	Matrix Metalloproteinase 2 (Gelatinase A)IBA 01/2018
1	polypropylene glycol (poly(propylene oxide))IBA 01/2018
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 01/2018
1	Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric 01/2018
1	4- (3- amino- 4- (2,4,5- trifluorophenyl)butanoyl)- 3- (tert- butoxymethyl)piperazin- 2- oneIBA 12/2017
1	Protein Kinases (Protein Kinase)IBA 10/2017
1	Adenosine Monophosphate (AMP)IBA 10/2017
1	celastrolIBA 05/2017
1	Death Domain ReceptorsIBA 05/2017
1	C-Reactive ProteinIBA 03/2017
1	Doxorubicin (Adriamycin)FDA LinkGeneric 02/2017
1	cucurbitacin BIBA 02/2017
1	Janus Kinase 2IBA 02/2017
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 02/2017
1	TerlipressinIBA 01/2017
1	CreatinineIBA 01/2017
1	Immunoglobulin G (IgG)IBA 01/2017
1	Immunoglobulins (Immunoglobulin)IBA 01/2017
1	SodiumIBA 01/2017
1	Histone Acetyltransferases (Histone Acetyltransferase)IBA 10/2016
1	triptolideIBA 10/2016
1	Vorinostat FDA Link 02/2016
1	trichostatin A (A 300)IBA 02/2016
1	theasinensin AIBA 02/2016
1	TNF-Related Apoptosis-Inducing LigandIBA 12/2015
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2015
1	CateninsIBA 10/2015
1	Glucagon-Like Peptide-1 Receptor AgonistsIBA 06/2015
1	X-Linked Inhibitor of Apoptosis ProteinIBA 02/2015
1	Inhibitor of Apoptosis ProteinsIBA 02/2015
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2015

Therapy/Procedure

2	Therapeutics 01/2018 - 01/2014
1	Injections 01/2018